mpc-11 cells Search Results


94
Bio X Cell isotype control igg2b
( A ) Schematic outline of the study. Created in BioRender. Trink, J. (2025) https://BioRender.com/2rod2yk ( B ) Fα2M significantly reduced fibrosis measured as trichrome, PSR, and fibronectin, as well as the myofibroblast marker α–smooth muscle actin (α-SMA). ( C ) Treatment with Fα2M also prevented Smad3 and FAK activation (measured by phosphorylation at S473/475 and Y397, respectively), as well as increased YAP expression compared with control <t>IgG1</t> ( n = 7–9; * P < 0.05, ** P < 0.01, **** P < 0.0001; # P < 0.05 significant by t test; scale bar represents 20 μm).
Isotype Control Igg2b, supplied by Bio X Cell, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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94
Bio X Cell anti igg
( A ) Schematic outline of the study. Created in BioRender. Trink, J. (2025) https://BioRender.com/2rod2yk ( B ) Fα2M significantly reduced fibrosis measured as trichrome, PSR, and fibronectin, as well as the myofibroblast marker α–smooth muscle actin (α-SMA). ( C ) Treatment with Fα2M also prevented Smad3 and FAK activation (measured by phosphorylation at S473/475 and Y397, respectively), as well as increased YAP expression compared with control <t>IgG1</t> ( n = 7–9; * P < 0.05, ** P < 0.01, **** P < 0.0001; # P < 0.05 significant by t test; scale bar represents 20 μm).
Anti Igg, supplied by Bio X Cell, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 94 stars, based on 1 article reviews
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90
Harlan Laboratories mpc-11 murine myeloma cells
( A ) Schematic outline of the study. Created in BioRender. Trink, J. (2025) https://BioRender.com/2rod2yk ( B ) Fα2M significantly reduced fibrosis measured as trichrome, PSR, and fibronectin, as well as the myofibroblast marker α–smooth muscle actin (α-SMA). ( C ) Treatment with Fα2M also prevented Smad3 and FAK activation (measured by phosphorylation at S473/475 and Y397, respectively), as well as increased YAP expression compared with control <t>IgG1</t> ( n = 7–9; * P < 0.05, ** P < 0.01, **** P < 0.0001; # P < 0.05 significant by t test; scale bar represents 20 μm).
Mpc 11 Murine Myeloma Cells, supplied by Harlan Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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90
BioGro Technologies Inc mpc-11 cells
( A ) Schematic outline of the study. Created in BioRender. Trink, J. (2025) https://BioRender.com/2rod2yk ( B ) Fα2M significantly reduced fibrosis measured as trichrome, PSR, and fibronectin, as well as the myofibroblast marker α–smooth muscle actin (α-SMA). ( C ) Treatment with Fα2M also prevented Smad3 and FAK activation (measured by phosphorylation at S473/475 and Y397, respectively), as well as increased YAP expression compared with control <t>IgG1</t> ( n = 7–9; * P < 0.05, ** P < 0.01, **** P < 0.0001; # P < 0.05 significant by t test; scale bar represents 20 μm).
Mpc 11 Cells, supplied by BioGro Technologies Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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European Collection of Authenticated Cell Cultures igg2b isotype control ab mpc11
( A ) Schematic outline of the study. Created in BioRender. Trink, J. (2025) https://BioRender.com/2rod2yk ( B ) Fα2M significantly reduced fibrosis measured as trichrome, PSR, and fibronectin, as well as the myofibroblast marker α–smooth muscle actin (α-SMA). ( C ) Treatment with Fα2M also prevented Smad3 and FAK activation (measured by phosphorylation at S473/475 and Y397, respectively), as well as increased YAP expression compared with control <t>IgG1</t> ( n = 7–9; * P < 0.05, ** P < 0.01, **** P < 0.0001; # P < 0.05 significant by t test; scale bar represents 20 μm).
Igg2b Isotype Control Ab Mpc11, supplied by European Collection of Authenticated Cell Cultures, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


( A ) Schematic outline of the study. Created in BioRender. Trink, J. (2025) https://BioRender.com/2rod2yk ( B ) Fα2M significantly reduced fibrosis measured as trichrome, PSR, and fibronectin, as well as the myofibroblast marker α–smooth muscle actin (α-SMA). ( C ) Treatment with Fα2M also prevented Smad3 and FAK activation (measured by phosphorylation at S473/475 and Y397, respectively), as well as increased YAP expression compared with control IgG1 ( n = 7–9; * P < 0.05, ** P < 0.01, **** P < 0.0001; # P < 0.05 significant by t test; scale bar represents 20 μm).

Journal: JCI Insight

Article Title: Inhibition of cell surface GRP78 and activated α 2M interaction attenuates kidney fibrosis

doi: 10.1172/jci.insight.183998

Figure Lengend Snippet: ( A ) Schematic outline of the study. Created in BioRender. Trink, J. (2025) https://BioRender.com/2rod2yk ( B ) Fα2M significantly reduced fibrosis measured as trichrome, PSR, and fibronectin, as well as the myofibroblast marker α–smooth muscle actin (α-SMA). ( C ) Treatment with Fα2M also prevented Smad3 and FAK activation (measured by phosphorylation at S473/475 and Y397, respectively), as well as increased YAP expression compared with control IgG1 ( n = 7–9; * P < 0.05, ** P < 0.01, **** P < 0.0001; # P < 0.05 significant by t test; scale bar represents 20 μm).

Article Snippet: Three separate studies were conducted: (a) treatment with C38 (made in-house) or the isotype control IgG2b (BioXcell, BE0086) antibodies; (b) Fα2M (made in-house) or the isotype control IgG1 (BioXcell, BE0083) antibodies; or (c) P19 or scrambled control peptide (both made in-house).

Techniques: Marker, Activation Assay, Phospho-proteomics, Expressing, Control